I-Polyethylene Oxide (PEO) I-Polymer Enesisindo Esiphezulu Sama-Molecular | I-Sustainable Release Matrix Yamaphilisi Asebenzisa Ama-Hydrophilic | I-USP/EP/ChP Compliant

I-Polyethylene Oxide yethu Yebanga Lemithi (i-PEO) iyi-homopolymer engeyona i-ionic enesisindo esikhulu sama-molecule, encibilika emanzini etholakala ezinhlobonhlobo zamazinga e-viscosity (isisindo sama-molecule sisuka ku-100,000 kuya ku-7,000,000)Isebenza njengesithako esisebenziseka kalula samafomu omthamo oqinile womlomo. Izicelo ezibalulekile zifaka: i-matrix yokukhululwa okuqhubekayo (umswakama osheshayo kanye nokwakheka kwejeli amahora angaphezu kwe-10 ukukhishwa kwesidakamizwa), i-mucoadhesive yezinhlelo zokugcina ama-buccal kanye ne-gastro-retentive, isibopho sokuhlanganiswa kwe-granulation kanye nokucindezela okuqondile, kanye ne-ejenti yokwakha ifilimu yamafilimu amancane kanye nezingubo zedivayisi yezokwelapha. Ivumelana ne-USP-NF, EP, kanye ne-ChP pharmacopoeias nge-CDE registration F20220000511. Iqukethe umswakama osheshayo, amandla aphezulu okuvuvukala, izakhiwo ze-thermoplastic, kanye nemvelo engeyona i-ionic (ayinambitheki, ayinambala)

Xhumana nathi

Imininingwane Yomkhiqizo

I-Polyethylene Oxide Yebanga Lemithi (PEO)

Ukubuka Konke Komkhiqizo

I-Polyethylene Oxide (PEO) iyi-homopolymer engeyona i-ionic ye-ethylene oxide, emelelwa yifomula i-H(OCH2CH2)nOH, lapho u-n emele khona inani elimaphakathi lamaqembu e-oxyethylene asukela cishe ku-2,000 kuya ku-200,000. Iyi-polymer enesisindo esikhulu sama-molecule, encibilika emanzini esetshenziswa kabanzi njengesithako semithi ekwakhiweni kokukhululwa okulawulwayo, izihlanganisi ze-granulation, izembozo zefilimu, kanye nezinhlelo zokulethwa kwezidakamizwa ze-mucoadhesive..

Ubunikazi Bomkhiqizo:

Igama Lekhemikhali:I-Polyethylene Oxide
Inombolo ye-CAS:68441-17-8 / 25322-68-3
Inombolo Yokubhalisa ye-CDE:F20220000511
Ukuthobela Imithetho Ye-Pharmacopoeia:I-ChP (CP2020), i-USP-NF, i-EP
Ukubukeka:Okumhlophe kuya kokumhlophe, impuphu egeleza ngokukhululeka enephunga elincane le-ammonia
Ukuncibilika:Incibilika emanzini kanye nasezithambisweni eziningi ezivamile zezinto eziphilayo (i-acetonitrile, i-chloroform, i-dichloromethane); ayincibiliki kuma-hydrocarbon e-aliphatic, i-ethylene glycol, kanye ne-ethanol